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Image Search Results
Journal: Journal of Pharmacokinetics and Pharmacodynamics
Article Title: gPKPDSim: a SimBiology ® -based GUI application for PKPD modeling in drug development
doi: 10.1007/s10928-017-9562-9
Figure Lengend Snippet: A schematic workflow of how modelers and end-users employ gPKPDSim. The expert modeler develops the model in SimBiology ® and encapsulates it into a “Session” file, which can be launched in gPKPDSim by end-users. The Session file, once loaded in gPKPDSim, enables the end-user to perform different functionalities, including simulation, data fitting (parameter estimation), population simulation, and NCA. For some of these functionalities, the user must provide a dataset. All the functionalities are supported by features such as interactive visualization, and export of results as presentation-ready figures and Excel datasets. When the user completed their tasks, the session file can be saved for future use. Note that the end-user works exclusively in the environment of gPKPDSim
Article Snippet: Note that gPKPDSim provides PKPD M&S capabilities to users in an organization with access to
Techniques:
Journal: Journal of Pharmacokinetics and Pharmacodynamics
Article Title: gPKPDSim: a SimBiology ® -based GUI application for PKPD modeling in drug development
doi: 10.1007/s10928-017-9562-9
Figure Lengend Snippet: Description of the components within the gPKPDSim framework
Article Snippet: Note that gPKPDSim provides PKPD M&S capabilities to users in an organization with access to
Techniques: Generated
Journal: Journal of Pharmacokinetics and Pharmacodynamics
Article Title: gPKPDSim: a SimBiology ® -based GUI application for PKPD modeling in drug development
doi: 10.1007/s10928-017-9562-9
Figure Lengend Snippet: gPKPDSim: simulation functionality view. This view has multiple sections: 1 ) general settings (top left); 2 ) functionality-specific settings including simulation time and parameter values (bottom left); 3 ) plot settings including species from the SimBiology ® model and dataset groups and column headers (top right); 4 ) non-compartmental analysis (NCA, bottom right); 5 ) profile notes including a list of most recent simulations and their detailed summary (bottom middle); and 6 ) interactive plots (top middle). See “ ” for detailed description of each section
Article Snippet: Note that gPKPDSim provides PKPD M&S capabilities to users in an organization with access to
Techniques:
Journal: Journal of Pharmacokinetics and Pharmacodynamics
Article Title: gPKPDSim: a SimBiology ® -based GUI application for PKPD modeling in drug development
doi: 10.1007/s10928-017-9562-9
Figure Lengend Snippet: A summary of different settings in gPKPDSim
Article Snippet: Note that gPKPDSim provides PKPD M&S capabilities to users in an organization with access to
Techniques: Selection, Variant Assay